Let $p=y^2$, $q=xy$, $r=-x^2$ and $u=f(p,q,r)$ where $f$ has continuous second order partial derivatives. Calculate $u_{xy}$ in terms of $p,q,r$ and partial derivatives of $f$ with respect to these variables.
Anyone can guide me for this kind of question so that I can do for all similar kinds?
My final result is : $$\frac{2y^2d^2(u)}{dqdp} -\frac{4xyd^2 (u)}{drdp} + \frac{du}{dq} +\frac{xyd^2(u)}{dq^2} -\frac{2x^2d^2(u)}{drdq}$$
You have $u=f(y^2,xy,-x^2)$. Then $u_x=y\frac {\partial f(p,q,r)}{\partial q}-2x\frac {\partial f(p,q,r)}{\partial r}$ by the chain rule. Now take the partial with respect to $y$