What applications did Laplace have in mind when he said (in 1812) that probability had become "the most important object of human knowledge"?

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"It is remarkable that a science which began with the consideration of games of chance should have become the most important object of human knowledge." -- Laplace, Théorie Analytique des Probabilitiés, 1812.

What new applications of probability was Laplace referring to here, in 1812, when he declared that probability had become the most important object of human knowledge? What was probability used for at that time?