I don't know much about homology theory, but the following question pops up in my mind and it may have some ambiguities.
Suppose $M$ is a finite-dimensional manifold with non-empty boundary $\partial (M)$. Now suppose $N= M-\partial(M)$ with induced topology from $M$. What is the relation between homology groups of $M$ and $N$?
I think I have a sketch that $M \setminus \partial M \hookrightarrow M$ induces an equivalence in Homology, but I didn't check all the details. So please delete it if it's wrong. If someone works out the details, please post your answer, I'll delete mine then.