If $(x^2+y^2)^3=4x^2y^2,$ then $r=\sin 2\theta$ for some $\theta$.
Using $r^2=x^2+y^2, x=r\cos\theta,y=r\sin\theta$, it's easy to get $r^2=\sin^22\theta$. But I don't know what to do next, since $r$ could be negative in $r=\sin2\theta.$
Actually the original problem is to show that the affine variety $V((x^2+y^2)^3-4x^2y^2)$ is contained in the four-leaved rose, whose polar equation is certainly $r=\sin 2\theta$. (Exercise 7(b), section 1.2, Ideals, Varieties and Algorithms, 3rd edition, David Cox etc.)


Allowing $r$ to take both nonnegative and negative values, the graphs of $r=\sin2\theta$ and $r=-\sin2\theta$ (on $0\le\theta<2\pi$) are identical—they contain the same set of geometric points in the plane—though they are traced out differently. For $r=\sin2\theta$, as $\theta$ increases from $0$ to $2\pi$, the graph traces the first quadrant petal, then the fourth quadrant petal, then the third quadrant petal, and finally the second quadrant petal. For $r=-\sin2\theta$, as $\theta$ increases from $0$ to $2\pi$, the graph traces the third quadrant petal, then the second quadrant petal, then the first quadrant petal, and finally the fourth quadrant petal.
edit Here's what I mean:
Since the sets of points in the plane described by $r=\sin2\theta$ and $r=-\sin2\theta$ are identical, giving only one of them is sufficient to describe the same set of points as $(x^2+y^2)^3=4x^2y^2$. That's what lets us go from $r^2=\sin^22\theta$ and its equivalent of $r=\pm\sin2\theta$ to only $r=\sin2\theta$.