Are the two graphs isomorphic?
$$G_1=\begin{bmatrix} a & b & c & d & e & f \\ b & a & a & c & d & a \\ c & c & b & e & f & d \\ f & & d & f & & e \end{bmatrix}\ \quad\quad G_2=\begin{bmatrix} u & v & w & x & y & z \\ v & u & v & u & x & u \\ x & w & x & w & z & w \\ z & & z & y & & y \end{bmatrix}$$
$a,b,c$ creates a triangle in $G_1$, but no triangle is created in $G_2$.
Is that enough to claim that they are not isomorphic?
This is a good example of two graphs with the same degree sequence $(3,3,3,3,2,2)$ which are not isomorphic. As the question states, the existence of the two triangles in $G_1$ and their absence in $G_2$ is proof that the two graphs are not isomorphic.
Here they are in graphical form: