Combinatorial proof of $\frac{(2n)!}{2^n \times n!} \in \mathbb{N}$
My try: Suppose there are $n$ families $F1,F2,F3,..Fn$ containing couples(Wife and Husband pair). So there are total $2n$ people.
We have $P=(2n)!$ as number of ways to arrange them in a line.
Now what is the combinatorial significance of $2^n \times n!$?
My thought is this:
Let there are $n$ different rooms. Each room should be accommodated with one person and no two rooms contain same family members. Thus first room can be occupied in $2$ ways, say from family $F1$ with either of Husband or Wife.Second room can also be occupied in $2$ ways say from $F2$ and so on. So total $2^n$ ways and these people can be arranged in $n!$ ways. Hence total $$Q=2^n \times n!$$
Any way to proceed from here to say the ratio $\frac{P}{Q}$ is an integer?
$\displaystyle \frac{(2n)!}{2^n \times n!}~$ happens to be the answer to the following problem:
How many distinct ways are there of forming $~n~$ pairs from $~2n~$ people, selecting the pairs without replacement, where the order that the pairs are formed is deemed irrelevant.
Therefore, the expression has to be an integer.
One (inelegant) way of verifying the answer is to consider the equivalent expression:
$$\frac{1}{n!} \times \left[ ~\binom{2n}{2} \times \binom{2n-2}{2} \times \cdots \times \binom{4}{2} \times \binom{2}{2} ~\right]. \tag1 $$
In (1) above, the RHS represents forming the first pair, from $~2n~$ people, then forming the next pair, and the next, and so on.
In (1) above, the LHS represents the over-counting adjustment factor needed to compensate for the fact that there are $~n!~$ ways of ordering the formation of any specific (i.e. distinct) group of $~n~$ pairs.