Two half circles and a full circle fit inside a larger quarter circle as shown in the diagram. The centers of the two half circles are on the two sides of the quarter circle, respectively.

Prove that the triangle formed by the centers of three smaller circles, $\triangle O_1O_2O_3$, is a right triangle.
I was able to apply the Pythagorean formula to a few triangles involving the radii of the inscribed circles and proved that the ratios of the three radii are 1:2:3. Then, the centers of the three circles form a triangle with side-length ratios 3:4:5, hence, a right triangle.
On the other hand, I feel the proof may be an overkill, and evaluating the three radii explicitly may be unnecessary. There ought to be clean geometric solutions to show directly that the vertex $O_3$ is of a right angle, which I am not sure how to figure out.



Given the quarter circle with $O$ as the center of the arc, and given semicircles with centers $O_1$ and $O_2$ on the two straight sides of the quarter circle such that $O_1$ and $O_2$ both are tangent to the arc of the quarter circle and such that $O_1$ and $O_2$ are tangent to each other.
This is based on the figure in the question, except that we do not assume that $O_1$ is the midpoint of one side of the quarter circle.
Let the radii of the quarter circle, the semicircle about $O_1$, and the semicircle about $O_2$ be $r,$ $r_1,$ and $r_2$ respectively.
Let $P$ be the fourth vertex of the rectangle that has three of its vertices at $O,$ $O_1,$ and $O_2.$ The sides of this rectangle are $OO_1 = r - r_1$ and $OO_2 = r - r_2.$ The diagonals are $OP = O_1O_2 = r_1 + r_2.$
Let $P_1$ be the point of intersection of the semicircle about $O_1$ with $O_1P$ and $P_2$ be the point of intersection of the semicircle about $O_2$ with $O_2P.$ Then $PP_1 = r - r_1 - r_2 = PP_2.$ Moreover, the distance from $P$ to the arc of the quarter circle is $r - (r_1 + r_2) = r - r_1 - r_2.$
Then a circle of radius $r - r_1 - r_2$ about $P$ is tangent to the quarter circle and to the semicircles about $O_1$ and $O_2.$ Therefore $P$ is $O_3$ in the figure, the center of the circle inscribed between the two semicircles and the quarter circle.
Since $O_3$ is a vertex of the rectangle $OO_1O_3O_2,$ the triangle $\triangle O_1O_3O_2$ is a right triangle. $\square$