Let AB be the diameter of a semi circumference. A point M is marked over the semi circumference, and a point K over AB. Draw circumference with center P that passes by the points A, M and K, and another circumference with center Q that passes by the points M, K and B. Show that M, K, P and Q are concyclic.
What I´ve tried so far is, as the sides of the quadrilateral are radii, the triangles APK and BQK are isosceles. Then, the line that connects the centers of both circles is also the height of both triangles that passes trough the side MK. That shows that the diagonal of the quadrilateral intersect at right angles, which turns the problem to showing that the median of one of the triangles intersects at a right angle the side oposite of the other triangle.
Also, the problem reduces to showing that the triangle QMP has a right angle at M. This can be shown by proving tha te angle MPQ is equal to MKQ.

This might have a simple solution computing angles, but with so many circles and demanding to prove that points were concyclic, this problem looks ideal for inversion.
If you invert with center at $K$ and radius $1$ (the radius is not important), let $A'$, $B'$ and $M'$ be the inverses of $A$, $B$ and $C$, respectively.
Call $C$ the first circle, $C_1$ the circle through $AMK$ and $C_2$ the circle through $BMK$.
The inverse of $C_1$ is the line $M'A'$, and the inverse of $C_2$ is the line $M'B'$.
Since $C$ is symmetric with respect to $AB$, then $C$ transforms into a circle $C'$ that is also symmetric with respect to the line $A'B'$.
Therefore the lines $M'A'$ and $M'B'$ are perpendicular, because $A'B'$ is a diameter of $C'$.
Now, the image $P'$ of $P$ is the reflection $K_1$ of $K$ with respect to the line $M'B'$. The image $Q'$ of $Q$ is the reflection of $K$ by the line $M'A'$.
Since these two lines are perpendicular, then $P'$, $M'$, and $Q'$ are collinear.
Therefore, their pre-images are concyclic with $K$.
Alternative ending of the inversion.
Since the lines $M'A'$ and $M'B'$ are perpendicular (since $A'B'$ is a diameter of $C'$). Then the circles $C_1$ and $C_2$ intersect perpendicularly. Therefore $PM$ is perpendicular to $QM$. By symmetry of $PMQK$ it follows that $PK$ is perpendicular to $QK$. Therefore, $PMQK$ is cyclic.