How to calculate effect of different variables/parameters on a quantity?

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I am developing a game for iOS. In the game I have around eight different parameters that directly affect the score of the player. We can say that these eight variables decide the difficulty of the game and hence score. Is there any way that I can combine these variables to produce a combined affect on the score. I have seen Elo's method for chess games but that is not useful for me.I welcome any mathematical method to attain the desired results.