Given a set $S$ such that $|S|=N$ and $S$ contains exactly $K$ $0$s $(0<K <N)$ and $N-K$ $1$s, then exactly half of the subsets of $S$ contain an $odd$ number of 1s, $indepedent$ of the value of $K$.
I have the following proof for this:
Number of subsets formed with $N-K$ zeroes is $2^{N-K}$. For each of this subset the number of ways in which I can select an odd number ones is: $$\sum_{n=1}^{N/2}\binom{K}{2n-1}= 2^{K-1}$$ Then the total subsets with $odd$ number of one's is $2^{N-1}$.
However I was looking for an intuitive proof for this.
You need to assume that $K<N$, not that $K>0$: you want to be sure that there is at least one $1$. Call a subset of $S$ odd if it contains an odd number of ones and even otherwise.
First suppose that $N-K$ is odd. If $A$ is any subset of $S$, those $N-K$ ones are split between $A$ and $S\setminus A$, so exactly one of these complementary sets is odd. Since exactly one of each pair of complementary subsets of $S$ is odd, exactly half of the subsets of $S$ are odd.
Now suppose that $N-K$ is even. $S$ contains at least one $1$, so we may remove it to leave a set $S'$ with an odd number of ones. By the previous paragraph we know that half of the subsets of $S'$ are odd. Now look at the subsets of $S$ that include the $1$ that we removed to get $S'$. These are precisely the subsets of $S$ that we get by adding that missing $1$ to each of the subsets of $S'$. Doing so changes odd subsets of $S'$ to even subsets of $S$, and even subsets of $S'$ to odd subsets of $S$; half of the subsets of $S'$ are odd, so half of the subsets of $S$ that contain that missing $1$ are even, and hence the other half are odd. Thus, half of the subsets of $S$ that don’t contain that $1$ are odd, and half of those that do contain it are odd, and therefore half of the subsets of $S$ are odd.