Let $\alpha>1$ and let $f:\mathbb{R}^{n}\to \mathbb{R}$ be defined by $f(x)=|x|^{\alpha}$. Let $$H(x):=\partial_{x_{i}}\partial_{x_{j}}f (x).$$
How can one show that there exists some $C>0$ such that $$\text{det}(H(x))\geq C$$ whenever $c_{2}>|x|>c_{1}>0$.
Write $H(x)=(h_{ij}(x))$, $1\leq i,j\leq n$. Direct calculations give $$h_{ij}(x)=\alpha|x|^{\alpha-4}\begin{cases} (\alpha-2)x^2_{i}+|x|^2,& i=j,\\\\ (\alpha-2)x_{i}x_{j},& i\neq j. \end{cases}$$
So, $H=\alpha|x|^{\alpha-4}(S+|x|^2 I_{n})$ where $S$ is the symmetric matrix $(\alpha-2)(x_i x_j)$. It is easy to show that $\text{det}(S)=0$. Does this simplify the problem ?
$rank(S)=1$ so $0$ is an eigenvalue of order $n-1$.
The last eigen value is given by $\lambda + (n-1)\times 0 = Tr(S)$ and $$\lambda = |x|^2$$
$S$ is equivalent to $diag(|x|^2,0,0,...0)$
And $S+|x|^2I_n$ is equivalent to $diag(2|x|^2,|x|^2,...|x|^2)$
Therefore $$det(S+|x|^2I_n)=2|x|^{2n}$$