Consider the system:
$$ \begin{split} \dot W &= i u(t)W(t)\\ \dot S &= e^{-rt}\sqrt{(1-u(t))W(t)} \end{split} $$
I would like to examine a system: $$ \begin{split} \dot x &= u(t)x(t)\\ \dot y &=\sqrt{(1-u(t))x(t)} \end{split} $$
Can someone tell me the transformations between $x(t)$ and $W(t)$, also between $y(t)$ and $S(t)$?
I do not see any particular reason why you would want to transform your differential equation. Why not solve it in the given formulation?
If $u(t)$ is a known input you can solve the first equation
$$\dfrac{dW}{W} = i u(t) dt \implies \ln |W|=\int_{t_0}^{t}iu(\tau)d \tau$$ $$\implies |W(t)| = \exp\left[ \int_{t_0}^{t}iu(\tau)d \tau\right]$$ $$\implies W(t) = \pm\exp\left[ \int_{t_0}^{t}iu(\tau)d \tau\right].$$
Then use this in the second differential equation and integrate the differential equation.
$$S(t)=\pm\int_{t_0}^{t}\exp(-r\tau)\sqrt{(1-u(\tau))W(\tau)}d\tau$$