The specific question is in the title but I'd also like to know how to calculate such probabilities of subsequences in general. I know I need to use the inclusion/exclusion principle but I don't know how to apply it in such cases.
Any and all advice is appreciated. :)

There are four positions you are interested in:
You then have recurrences (which you could instead write as a Markov chain transition matrix):
You can work through these to find $P_{10} = \frac{393}{1024}$ here
Other 4-flip target patterns may have different recurrences and slightly different values of $P_{10}$