Let $A$ be a matrix and $b$ be a strictly positive vector. Denote by $B=\text{diag}(b)$, a matrix with $b$ on its diagonal and zeros elsewhere. I am interested in the symmetric matrix $$ C = AB+(AB)'. $$
Now, consider the subspace $S:\sum_i x_i=0$. I want to find sufficient conditions on $A$ such that $C$ is negative definite on $S$, i.e. for all $x\in S$ we have $x'Cx\leq -d \left\Vert x\right\Vert $ for some $d>0$.
I can show that this is true if $A$ is full of ones except for the diagonal which is full of zeros. In this case, we can write $A=O-I$, where $O$ denotes a matrix full of 1 and $I$ the identity, and $$\begin{align} x'Cx &= x'((O-I)B+((O-I)B)')x \\ &= -2x'Bx \\ &< 0. \end{align}$$ for $x\neq 0$ and where I used the fact that $x'OBx=0$.
I can find other hollow matrices $A$ (zeros on the diagonal) such that $C$ seems negative definite but there are also counterexamples, mostly when $A$ has many zeros. I am hoping that a more general result exists. I'm mostly interested in matrices $A$ that are binary, so if a result exists for these matrices it would be great.
$$x^T C x = 2 x^T A B x$$ But $(B x)_j = b_j x_j$, so $B x$ can be any vector with the same signs as $x$. Now for any $i \ne j$, consider $x$ of the form $x_i = 1$, $x_j = -1$, $x_k=0$ otherwise. Then $(Ax)_i = a_{ii} - a_{ij}$. If $C$ is negative definite on the subspace $S$ for all $B$, it must be that $a_{ii} \le a_{ij}$.