This is an example from Discrete Mathematics and its Applications

I understand how to encrypt, the first step is to turn the letters into their numerical equivalents(same thing we had to do for shift ciphers). The author's justification for grouping these numbers into blocks of four digits is that 2525 < 2537 < 252525.
I understand what n is. n in RSA is the product of two primes, 43 and 59 in this case.
But why does n have to fall in the range of interval notation (2525, 252525)? Where do these two integers 2525 and 252525 come from?
I suppose it comes from the encoding procedure of having A - 00, B - 01, ... , Z - 25.