Every category theory reference says that the isomorphism in the title is a triviality. How so?
$$ \lim F \equiv \text{Hom}_{\hat{C}}(\text{pt}, F) \in \text{Set} $$
so
$$ \lim \text{Hom}_{\text{Set}}(S, F(\cdot)) = \text{Hom}_{\hat{C}}(\text{pt}, \text{Hom}_{\text{Set}}(S, F(\cdot))) = ? $$
I am aware of this definition: $$\lim F \simeq \left\lbrace (x_d)_{d \in D} \in \prod_{d \in D} F(d) | \forall (d_i \stackrel{\alpha}{\to} d_j) \in D : F(\alpha)(x_{d_j}) = x_{d_i} \right\rbrace $$
Here's another approach. If you know that limits commute and that products are limits, then you simply have to note that $\text{Hom}_{\text{Set}}(S, X) \simeq \prod_{s\in S}X$, then the result is just an example of commutation of limits.