Source: Miklos Bona, A Walk Through Combinatorics.
$$ \forall k\geq 2,\binom{2k-2}{k-1}\leq4^{k-1}.$$
The RHS is the upper bound of the Ramsey number $R(k,k)$.
How can I prove the inequality without using mathematical induction? I've merely expanded the LHS to obtain $\frac{(2k-2)!}{(k-1)!(k-1)!}$.
Consider a set $S$ with $2k-2$ elements. The set $S$ has $2^{2k-2}=4^{k-1}$ subsets. The number of subsets of S that have exactly $k-1$ elements is $\binom{2k-2}{k-1}$. Clearly the number of subsets of $S$ with $k-1$ elements is less than the total number of subsets of $S$. (@Did's answer is effectively the same as mine.)