I have two random variables $X$ and $Y$. I know the expected values $E\left[X\right]$ and $E\left[Y\right]$, as well as their respective variances $V\left[X\right]$ and $V\left[Y\right]$ (I have them actually tabulated from a curve fitting/regression analysis).
If I want to calculate $E\left[X\cdot Y\right]$, I've derived this equation. $$E\left[X\cdot Y\right]=E\left[X\right]\cdot E\left[Y\right]+C\left[X,Y\right]$$
The problem is I don't know the covariance $C\left[X,Y\right]$, but I do know if each random variable is independent, then the covariance is zero. Since I know the expected values and the variances, can demonstrate from the tabulated values the independence of $X$ and $Y$?
Clearly the expectation and variance of a random variable only tells you some things about that random variable, and not about how it may depend on another random variable.
Having two sets of expectations and variances can not indicate anything about how the respective variables depend on each other.
PS: Even knowing that the covariance is zero does not prove that the random variables are independent. Independent variables have zero covariance, but the converse does not necessarily hold.