Let $(R, m ,k)$ be a commutative Noetherian local ring. We denote by $E$ the injective envelope of $k$ and by $R^~$ the $m$-adic completion of $R$. For any module $M$ over $R$, we let $M^*=Hom_R(M,E)$.
Let $E_n=\{x\in E\mid m^nx=0\}$. Then $E_n\cong (R/m^n)^*$ and $E=\varinjlim E_n$, that is, the union of $E_n$ is $E$.
We have the following isomorphism chain: $$Hom_R(E,E)\cong (\varinjlim E_n)^*\cong lim_{\leftarrow}(E_n)^*\cong lim_{\leftarrow}(R/m^n)^{**}\cong lim_{\leftarrow}R/m^n=R^~$$ Here, we have used that $(R/m^n)^{**}\cong R/m^n$ since $R/m^n$ has finite length.
Question 1: Is the isomorphism $Hom_R(E,E)\cong R^~$ of $R$-modules obtained above a ring isomorphism? If so, how to prove it?
I have found an interesting thing.
Let $\alpha: R\rightarrow R^~$ be the natural embedding. Let $\beta :R\rightarrow End_R(E)$ be the $R$-homomorphism sending $r$ to $x \mapsto rx$. Denote by $\delta:End_R(E)\rightarrow R^~$ the isomorphism of Question 1. I think that, in general, $\delta\beta $ is not equal to $\alpha$. Let $ass(E)$ denote the set of associate primes of $E$. Since $ass(E)=\{m\}$, we have $ass(E)=Supp(E)=V(ann(E)) = \{m\}$. So, if $\dim_{Krull}(R) > 0$, then $ann(E)$ is not equal to $\{0\}$.
Question 2: When is $\beta$ injective?
Question 3: When does the identity $\delta\beta=\alpha$ hold true?
We will use
Now we can prove Claim 1.
The next questions also have simple answers.
So, what's wrong with the following claim by OP?
$$ ass(E)=Supp(E)=V(ann(E)) = \{m\} ?$$
The identity $ass(E) = \{m \}$ holds true by [1, Theorem 18.4.v] and the inclusions $ass(M) \subseteq Supp(M) \subseteq V(ann(M))$ are valid for any commutative ring $R$ and any $R$-module $M$. If $M$ is finitely generated, then we have $Supp(M) = V(ann(M))$, see [1, Remark of §4], but equality doesn't hold in general and this is the only problem. Indeed, it fails for instance if $R$ is a discrete valuation ring and $E$ is the injective envelop of its residue field $k$ ($E = Frac(R)/R$ is not finitely generated in this case). Regarding the inclusion, $ass(M) \subseteq Supp(M)$ we also know that the minimal primes of $ass(M)$ are those of $Supp(M)$ if $R$ is Noetherian [1, Theorem 6.5]. In the context of the question, it is not difficult to show that, indeed, $ass(E) = Supp(E)$ (one can use, e.g., [1, Theorem 18.4.v]).
[1] H. Matsumura, "Commutative Ring Theory", 1989.