Lie's second theorem says that if $G$ is a simply connected Lie group, then every isomorphism $\Phi$ of its Lie algebra $\mathfrak{g}$ lifts to an isomorphism $\phi$ of $G$, i.e. such that $d\phi_e = \Phi$ where we identify $\mathfrak{g}$ with $T_e G$, the tangent space to $G$ at the identity.
Now consider $G = \mathrm{SO}(3)$, which is not simply connected. Is there an explicit counterexample to Lie's second theorem in this case? That is, can we write down a Lie algebra isomorphism $\Phi$ of $\mathfrak{so}(3)$ which is not the differential of any isomorphism $\phi$ of $\mathrm{SO}(3)$?
I feel like, if $(\eta_1, \eta_2, \eta_3)$ is the usual basis of $\mathfrak{so}(3)$, where $[\eta_i, \eta_j] = \eta_k$ cyclically, then a map like $\Phi(\eta_1)=\eta_2$, $\Phi(\eta_2)=\eta_1$, $\Phi(\eta_3)=-\eta_3$ ought to work, but I can't figure out how to prove there is no such group isomorphism $\phi$. I've been trying to find $t_1, t_2, t_3 \in \mathbb{R}$ and a relation involving $(e^{t_1 \eta_1}, e^{t_2 \eta_2}, e^{t_3 \eta_3})$ that is not satisfied by $(e^{t_1 \eta_2}, e^{t_2 \eta_1}, e^{-t_3 \eta_3})$ but I can't come up with one.
See $SU(2)$ as the group of quaterninons with norm $1$. Let$$\operatorname{Im}\mathbb{H}=\{ai+bj+ck\in\mathbb{H}\,|\,a,b,c\in\mathbb{R}\}$$and, for each $q\in SU(2)$, let $\varphi(q)\colon\operatorname{Im}\mathbb{H}\longrightarrow\operatorname{Im}\mathbb{H}$ be the map defined by $\varphi(q)(v)=q^{-1}vq$. Then $\operatorname{Im}\mathbb{H}\simeq\mathbb{R}^3$ and $\varphi$ is a surjective group homomorphism from $SU(2)$ onto $SO(3,\mathbb{R})$, whose kernel is $\pm1$. Then $D\varphi_1\colon\mathfrak{su}(2)\longrightarrow\mathfrak{so}(3,\mathbb{R})$ is a Lie algebra isomorphism and its inverse is a representation of $\mathfrak{so}(3,\mathbb{R})$ in $\mathbb{C}^2$. But you cannot lift it to $SO(3,\mathbb{R})$, since $SU(2)$ and $SO(3,\mathbb{R})$ are not isomorphic.