Consider a proximal operator,
$$ \operatorname{Prox}_{ \lambda f } \left( \mu x \right) := \arg \min_{u} \lambda f \left( u \right) + \frac{1}{2} {\left\| u - \mu x \right\|}_{2}^{2}.$$
What is the partial derivative of the proximal operator w.r.t. $\lambda$ and $\mu$, i.e.
$$\frac{\partial\operatorname{Prox}_{ \lambda f } \left( \mu x \right)}{\partial\lambda}, \quad \frac{\partial\operatorname{Prox}_{ \lambda f} \left( \mu x \right)}{\partial\mu}?$$
If the general case is not solvable, is it possible to compute the derivative if we restrict $f$ to be an $L_p$ norm?
The prox operator takes a point (vector) and maps it into a subset of your vector space, this mapping might be empty, a singleton or a set. Therefore the prox operator is not differentiable.
The following example is from the book by Beck. Consider the following functions: \begin{align} g_1(x) &=0, \\ g_2(x)&=\begin{cases} 0 & x \neq 0\\ - c & x=0, \end{cases}\\ g_3(x)&=\begin{cases} 0 & x \neq 0\\ c & x=0, \end{cases} \end{align} then the prox of the previous functions is:
\begin{align} \text{prox}_{g_1}(x)&=\{x\}.\\ \text{prox}_{g_2}(x)&=\begin{cases} \{0\}, & |x| < \sqrt{2c},\\ \{x\}, & |x| > \sqrt{2c}, \\ \{0,x\}, & |x| = \sqrt{2c}. \end{cases}\\ \text{prox}_{g_3}(x)&=\begin{cases} \{0\} & x \neq 0,\\ \emptyset & x=0. \end{cases} \end{align}
On the other hand, the Moreau envelope, defined as $$M^{\mu}_f(x) = \inf_{y}\bigg\{f(y)+\frac{1}{2\mu} ||x-y||^2 \bigg\},$$ is a smooth map (in fact $\mu$ is called the smoothing parameter), therefore it makes sense to talk about differentiability. The derrivate of the Moreau envelope is $$\nabla M^{\mu}_f(x) = \frac{1}{\mu}(x - \text{prox}_{\mu f}(x)).$$
You can read more on the excellent books by Beck (Ch. 6) and Bauschke & Combettes (Ch. 12).