Find the probability that the connection of two vertices of a rectangular prism are skew.

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R denotes a rectangular prism, S denotes the set of lines L where L passes through two of the vertices of R. If two random lines are chosen from S, what is the probability that these two lines are skew?

I know that there are 28 possible lines in S. I tried to use combinatorics to solve this, but I got confused because there was repetitions.