Let $F: \mathbb R^n \to \mathbb R^n$ be a smooth vector field. I conjecture that $F$ is irrotational iff its Jacobian is a symmetric matrix.
In two and three dimensions, this seems clear from Green and Stokes theorem. I conjecture this is true for any $n$ dimensions.
Is this true? If so, it raises a few additional questions:
We normally use curl to describe a vector field. Can we use curl, or at least its magnitude, to describe matrices? That is, can we use the magnitude of curl to measure how much a matrix rotates, or how non symmetric it is? Can we use the components of curl to tell us the nature of this asymmetry / rotation?
Would it be correct to say that for any two distinct dimensions $i, j$, that the measure of asymmetry $A_{ij} - A_{ji}$ is a measure of how much the matrix rotates a vector in the $i,j$ plane?
There are many well known types of matrices with interesting properties (e.g. orthogonal). If the Jacobian of $F$ is an "interesting" matrix, what does it tell us about $F$? For example, if $J(F)$ is orthogonal?
Part of the question here is to make sense of what irrotational means in $\Bbb R^n$ for $n \geq 4$. One way to approach a definition is as follows.
Recall that a smooth vector field ${\bf X} = (P, Q, R)$ with domain $\Bbb R^3$ is irrotational, i.e., has curl ${\bf 0}$, if and only if it is conservative, that is, if and only if $${\bf X} = \operatorname{grad} \varphi$$ for some (smooth) function $\varphi : \Bbb R^3 \to \Bbb R$, equivalently, $$\varphi_x = P, \qquad \varphi_y = Q, \qquad \varphi_z = R .$$ Indeed, since $\varphi$ is smooth, Clairaut's Theorem implies that the components $P, Q, R$ of $\bf X$ satistfy the differential condition $$Q_x = \varphi_{yx} = \varphi_{xy} = P_y$$ and its analogues for other pairs of independent variables, $P_z = R_x$ and $R_y = Q_z$. But if these $3$ conditions hold, then $$\operatorname{curl} {\bf X} = (R_y - Q_z, P_z - R_x, Q_x - P_y) = {\bf 0} .$$
In this case, the Jacobian of $\bf X$, regarded as a map $\Bbb R^3 \to \Bbb R^3$ is simply the (automatically symmetric) Hessian of the potential function $\varphi$: $$\operatorname{Jac} ({\bf X}) = \pmatrix{ P_x & P_y & P_z \\ Q_x & Q_y & Q_z \\ R_x & R_y & R_z } = \pmatrix{ \varphi_{xx} & \varphi_{xy} & \varphi_{xz} \\ \varphi_{xy} & \varphi_{yy} & \varphi_{yz} \\ \varphi_{xz} & \varphi_{yz} & \varphi_{zz}}$$
In $n$ dimensions the situation is essentially the same: If a vector field ${\bf X} = (X^1, \ldots, X^n)$ with domain $\Bbb R^n$ is conservative, say, with potential $\varphi$, then for all indices $i, j$ we have $$\partial_{x_j} X^i = \partial_{x_j} \partial_{x_i} \phi = \partial_{x_i} \partial_{x_j} \phi = \partial_{x_i} X^j,$$ a total of $\frac{1}{2} n (n - 1)$ nontrivial conditions. So it's natural to define the $n$-dimensional analogue of curl to be a map $\alpha$ that takes a vector field $\bf X$ to to the collection $\partial_{x_i} X^j - \partial_{x^j} X^i$ of functions, where $1 \leq i < j \leq n$, and we can declare ${\bf X}$ to be irrotational if $\alpha({\bf X}) = (0, \ldots, 0)$. Again it turns out that vanishing of $\alpha({\bf X})$ is not only necessary but also sufficient to guarantee that ${\bf X}$ is a gradient. As in the $3$-dimensional case, the conditions $\partial_{x_i} X^j = \partial_{x_j} X^i$ are exactly that the Jacobian $\operatorname{Jac} ({\bf X})$ of $\bf X$ (at each point) is symmetric (hence equal to the Hessian of the potential), giving the desired equivalence of conditions: $$\boxed{\textrm{$\bf X$ is irrotational} \Leftrightarrow \textrm{$\operatorname{Jac}({\bf X})$ is symmetric}} .$$
There are two more systematic ways to organize the above construction:
(1) Regard $\alpha$ as the map taking a vector field ${\bf X}$ to the skew-symmetrization of its Jacobian: $$\operatorname{Alt} \operatorname{Jac} ({\bf X}) = \frac12 [\operatorname{Jac} ({\bf X}) - (\operatorname{Jac} ({\bf X}))^\top].$$ This viewpoint makes the desired equivalence of conditions more or less immediate.
(2) Regard the map $\alpha$ as taking a vector field ${\bf X} = \sum_i X^i {\bf e}_i$ to the bivector field, $$\alpha({\bf X}) := \sum_{i < j} (\partial_{x_i} X^j - \partial_{x^j} X_i) \, {\bf e}_i \wedge {\bf e}_j .$$ From this point of view $\alpha$ fits into a natural sequence of operators that can be identified with the exterior derivative on Euclidean space.
Example In dimension $3$, there is a canonical identification between vectors and bivectors on $\Bbb R^3$, namely, $$ {\bf i} \leftrightarrow {\bf j} \wedge {\bf k}, \qquad {\bf j} \leftrightarrow {\bf k} \wedge {\bf i}, \qquad {\bf k} \leftrightarrow {\bf i} \wedge {\bf j} , $$ and under this identification we can think of $\alpha$ as a map that takes vector fields to vector fields, and this map is exactly the usual curl. Also using a similar identification for $\operatorname{div}$ lets us regard the sequence of operators mentioned in (2) with the usual sequence $\operatorname{grad}, \operatorname{curl}, \operatorname{div}$ on $\Bbb R^3$.
Jacobians satisfying matrix conditions
It turns out that the symmetric part $$\operatorname{Sym} \operatorname{Jac} {\bf X} = \frac12 [\operatorname{Jac} ({\bf X}) + (\operatorname{Jac} ({\bf X}))^\top]$$ of the Jacobian of ${\bf X}$ measures exactly how the metric structure of $\Bbb R^n$ distorts infinitesimally when we let points "flow" along ${\bf X}$ (more precisely, we can identify that symmetric part with the Lie derivative $\mathcal{L}_{\bf X} \bar g$ of the flat metric $\bar g$ on $\Bbb R^n$ by $\bf X$.) So, a vector field whose Jacobian (at every point) has zero symmetric part---equivalently, whose Jacobian is skew-symmetric---is exactly one under whose flow the metric structure is preserved. Such vector fields are called Killing (vector) fields.
Similarly, the trace $\operatorname{tr} \operatorname{Jac} {\bf X}$ of the Jacobian of ${\bf X}$ measures how volume distorts infinitesimally when we let points flow "along" ${\bf X}$, and so a vector field that has tracefree Jacobian (at each point) is exactly one under which volume is preserved.
Remark In the above presentation I specifically treated the case that the domain of the vector field is all of $\Bbb R^n$. If that's not the case, most of the above still holds with one important exception: It's still always true that if $\bf X$ is conservative then it satisfies $\alpha(\bf X) = {\bf 0}$ (in dimension $3$, $\operatorname{curl} {\bf X} = {\bf 0}$), but the converse need only hold when the domain of $\bf X$ is simply connected, or, roughly speaking, has no "holes" of a certain type. This observation can be turned around to use $\alpha$ to detect holes in a set and is the beginning of de Rham cohomology.