Is there a notion of discriminant in general systems of nonlinear algebraic equations?

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Given a system of nonlinear algebraic equations, is there a general way to define a discriminant? As far as I know you can define a discriminant in some cases, e.g. when you have elliptic equations and this is somehow related to the general theory of elliptic curves.

Is this only possible when you work case-by-case? Do there exist any theorems that render the construction of a discriminant impossible in some other cases?