Let $V$ be a quasiprojective real variety. My intuition tells me that this type of space with the Euclidean topology has the property that path-connectedness and connectedness are equivalent. Is this true? If so, is there an easy argument for this?
I would expect the result does not change if I replace real with complex or quasiprojecive variety with semi-algebraic set.
Yes! One easy argument is that any such variety admits a triangulation, and any set admitting a triangulation is locally path connected which implies that path connected is equivalent to connected.
The first claim about triangulations can be sourced to Hironaka. Here is his original presentation, which is a fair bit more general than you will need:
In fact, a version of this claim is true more generally in any o-minimal geometry:
Morally, any sort of algebraic structure is too well-behaved for anything "topologically awful" to happen.