It is known that any item produced by a certain machine will be defective with probability $0.01$, independently of any other item.
What is the probability that a lot of $100$ items will contain more than $2$ defective items? You should use a suitable approximation and state the parameter values.

We know
$$p = .01$$ $$n = 100$$
And our interest is $$x > 2$$
I would use the binomial distribution because the probability of success ( p = .01) is constant and the item is either "defective" or "non-defective". You're interested in:
$$P(x>2)=P (x\geq 2.5)=P (x\geq 3)$$
You can estimate this binomial distribution using the Poisson approximation, because we have very large $n$ and very small $p$, The parameters are: $$n*p = 1$$
For a poison distribution we know that:
$$P(x) =\frac{e^{-\text{np}} \text{np}^x}{x!}$$
Thus,
$$P (x > 2)\approx \frac{\frac{1}{e}*1^x}{x!}$$ $$1-P (x\leq 2)\approx\frac{\frac{1}{e}*1^x}{x!}$$ $$ P (x\leq 2)\approx 1-(1/e\left(\frac{1}{2!}+\frac{1}{1!}+1\right))$$
Much thanks and appreciation to David Quinn for giving me some clarification, I hope I did this correctly for you.
In addition, you can use "PoissonCDF" in a graphine calculator and doing 1 - probability, where parameters Lambda = 1, lower bound = 0 and upper bound = 2. Doing so, 1 - .919699 = .0803 which matches the results produced in the R code above.