I was surprised that I couldn’t find this question answered on this site (not for lack of trying). I need the result for answering Probability of random sphere lying inside the unit ball, so I’m posting it as a separate question and answer for future reference.
What is the expected volume of the simplex formed by $n+1$ points independently uniformly distributed on $\mathbb S^{n-1}$?
MathWorld has the answers $\frac3{2\pi}$ for $n=2$ under Circle Triangle Picking and $\frac{4\pi}{105}$ for $n=3$ under Sphere Tetrahedron Picking, but the general result is surprisingly hard to find.
The question is answered in Isotropic Random Simplices by R. E. Miles (Advances in Applied Probability, 3(2), 353–382) in Theorem $2$ on p. $362$. More generally, for $i$ points independently uniformly distributed in the interior of the $n$-ball and $j$ points independently uniformly distributed on its boundary (the sphere $\mathbb S^{n-1}$), with $1\le r:=i+j-1\le n$ so that the points almost surely form an $r$-simplex, the moments of the volume $\Delta$ of this simplex are
$$ E\left[\Delta^k\right] =\\ \frac1{r!^k}\left(\frac n{n+k}\right)^i\frac{\Gamma\left(\frac12(r+1)(n+k)-j+1\right)}{\Gamma\left(\frac12[(r+1)n+rk]-j+1\right)}\left(\frac{\Gamma\left(\frac12n\right)}{\Gamma\left(\frac12[n+k]\right)}\right)^r\prod_{l=1}^{r-1}\frac{\Gamma\left(\frac12[n-r+k+l]\right)}{\Gamma\left(\frac12[n-r+l]\right)}\;. $$
In our case, $i=0$, $j={n+1}$, $r=n$ and $k=1$, so the desired volume is
$$ A_n=\frac1{n!}\frac{\Gamma\left(\frac12n^2+\frac12\right)}{\Gamma\left(\frac12n^2\right)}\left(\frac{\Gamma\left(\frac12n\right)}{\Gamma\left(\frac12n+\frac12\right)}\right)^n\prod_{l=1}^{n-1}\frac{\Gamma\left(\frac12l+\frac12\right)}{\Gamma\left(\frac12l\right)}\;. $$
With
\begin{eqnarray} \Xi(n):=\frac{\Gamma\left(n+\frac12\right)}{\Gamma(n)} \end{eqnarray}
this becomes
$$ A_n=\frac1{n!}\Xi\left(\frac{n^2}2\right)\Xi\left(\frac n2\right)^{-n}\prod_{l=1}^{n-1}\Xi\left(\frac l2\right)\;. $$
Thus, with
\begin{array}{c|cc} n&\frac12&1&\frac32&2&\frac92&8\\\hline \Xi(n)&\frac1{\sqrt\pi}&\frac{\sqrt\pi}2&\frac2{\sqrt\pi}&\frac{3\sqrt\pi}4&\frac{128}{35\sqrt\pi}&\frac{6435\sqrt\pi}{4096}\\ \end{array}
we find
$$ A_2=\frac12\frac{\Xi(2)\Xi\left(\frac12\right)}{\Xi(1)\Xi(1)}=\frac3{2\pi} $$
and
$$ A_3=\frac1{3!}\frac{\Xi\left(\frac92\right)\Xi\left(\frac12\right)\Xi(1)}{\Xi\left(\frac32\right)\Xi\left(\frac32\right)\Xi\left(\frac32\right)}=\frac{4\pi}{105}\;, $$
in agreement with the MathWorld values, and also
$$ A_4=\frac1{4!}\frac{\Xi(8)\Xi\left(\frac12\right)\Xi(1)\Xi\left(\frac32\right)}{\Xi(2)\Xi(2)\Xi(2)\Xi(2)}=\frac{6435}{31104\pi^2}\;. $$