Is there any possibility to simplify the expression $\mathbb{E}[Y|(X_{1} + X_{2})]$? Assume that $\mathbb{E}[Y]$, $\mathbb{E}[X_{1}]$, $\mathbb{E}[X_{2}]$, $\mathbb{E}[(X_{1} + X_{2})]$ all exist. Is there a difference if $X_{1}$ and $X_{2}$ are not independent?
Can I simply write $\mathbb{E}[Y|(X_{1} + X_{2})] = \mathbb{E}[Y|X_{1}] + \mathbb{E}[Y|X_{2}]$?
Not generally.
Counterexample
Let $X_1, X_2$ be the result of two independent dice throws (six-sided, enumerated, unbiased). Further, let $Y:=X_1+X_2$.
Then
Therefore: $\mathsf E(Y\mid X_1+X_2) =\mathsf E(Y\mid X_1)+\mathsf E(Y\mid X_2)-7$