Let $M$ be a smooth manifold and $X: M\to TM$ a smooth vector field. Then one of the fundamental theorem of differential geometry tell us there is a smooth map $$ \alpha: \mathcal{D}(X)\to M $$ called the flow of $X$ where $\mathcal{D}(X)$ is the domain of the flow. Moreover We have $$ \mathcal{D}(X) = \bigcup_{t\in\mathbb{R}}\{t\}\times\mathcal{D}_t(X)\subset \mathbb{R}\times M $$ where $\mathcal{D}_t(X)$ is the set of points $p\in M$ such the maximal integral curve of $X$ through $p$ is defined at least in the interval $[0, t]$.
Is there an $\epsilon>0$ such that for every $\left|t\right| < \epsilon$ we have $\mathcal{D}_t(X) = M$? In words, is there a minimal bound for the lifetime of a maximal integral curve?
(The negation would be for every $\epsilon > 0$ there exists a maximal integral curve $c: I\to M$ with domain strictly included in $]-\epsilon, \epsilon[$.)
I guess that if the negation holds, one can give an example with $M = \mathbb{R}^n$ or an open subset of it.
The answer to your question is no, as the counterexample in the comments shows. In fact, such an $\varepsilon$ never exists unless the vector field is complete, meaning that every integral curve exists for all time. The following is a paraphrase of Lemma 9.15 in my Introduction to Smooth Manifolds (2nd ed.):
(By the way, your statement in parentheses is the negation of the preceding statement, not the converse.)