Given the following Bayes network:
how can I calculate $\Pr(C|\lnot A,E)$?
I think first we need to use Bayes theorem, then we can use chain rule: $$ \Pr(C|\lnot A, E)=\frac{\Pr(\lnot A, E|C)\cdot\Pr(C)}{\Pr(\lnot A,E)}=\\\frac{\Pr(\lnot A, E,C)\cdot\Pr(C)}{\Pr(\lnot A,E)}=\\ \frac{\Pr(\lnot A)\Pr(C|A)\Pr(E|C)\Pr(C)}{\sum_{C\in \{T,F\}}\Pr(\lnot A, C, E)} $$
Am I on the right track?

$P(\neg A,C,E)$ is the marginalization of the joint distribution $$\sum_{B,D} P(\neg A,B,C,D,E) $$ and the joint is given via the network (which you've already used).
Joint probability:
$P(\neg A,B,C,D,E) = P(\neg A)P(C\mid\neg A) P(E\mid C) P(B) P(D\mid \neg A,B)$.